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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HERC5
All Species:
7.58
Human Site:
S428
Identified Species:
16.67
UniProt:
Q9UII4
Number Species:
10
Phosphosite Substitution
Charge Score:
0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UII4
NP_057407.2
1024
116852
S428
S
P
A
C
L
T
G
S
F
L
R
K
R
R
T
Chimpanzee
Pan troglodytes
XP_001160851
1020
115010
S420
S
P
A
C
L
T
A
S
F
L
K
K
R
G
T
Rhesus Macaque
Macaca mulatta
XP_001100859
1050
117053
V427
A
N
T
I
N
G
V
V
Q
I
L
S
S
A
A
Dog
Lupus familis
XP_535652
1157
130960
S561
S
P
A
C
L
I
G
S
F
L
K
E
R
I
A
Cat
Felis silvestris
Mouse
Mus musculus
Q6PAV2
1057
118393
D427
V
E
I
A
N
E
I
D
G
T
F
S
S
S
G
Rat
Rattus norvegicus
Q5PQN1
1057
118521
D427
V
E
I
A
N
E
I
D
G
T
F
S
S
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508293
996
112121
Q416
L
I
Q
P
D
H
P
Q
I
A
Q
Q
V
A
A
Chicken
Gallus gallus
XP_001231234
1056
118760
D427
V
E
I
A
N
E
I
D
G
T
F
S
S
A
G
Frog
Xenopus laevis
Q2TAS2
751
86306
N209
L
S
C
F
V
D
E
N
T
P
I
T
G
T
N
Zebra Danio
Brachydanio rerio
A9JRZ0
765
87445
D224
G
A
A
G
V
P
A
D
D
P
R
V
Q
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40985
892
103438
R351
V
K
P
E
D
E
M
R
S
R
L
R
R
H
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
49.2
35.3
67.7
N.A.
34.6
35
N.A.
36.5
35.4
20.3
21.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
65.7
54.9
75.8
N.A.
55.6
55.9
N.A.
57.4
56.1
37.9
37.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
80
0
66.6
N.A.
0
0
N.A.
0
0
0
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
86.6
13.3
80
N.A.
0
0
N.A.
13.3
0
13.3
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
37
28
0
0
19
0
0
10
0
0
0
28
28
% A
% Cys:
0
0
10
28
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
19
10
0
37
10
0
0
0
0
0
0
% D
% Glu:
0
28
0
10
0
37
10
0
0
0
0
10
0
10
0
% E
% Phe:
0
0
0
10
0
0
0
0
28
0
28
0
0
0
0
% F
% Gly:
10
0
0
10
0
10
19
0
28
0
0
0
10
10
28
% G
% His:
0
0
0
0
0
10
0
0
0
0
0
0
0
10
10
% H
% Ile:
0
10
28
10
0
10
28
0
10
10
10
0
0
10
0
% I
% Lys:
0
10
0
0
0
0
0
0
0
0
19
19
0
0
0
% K
% Leu:
19
0
0
0
28
0
0
0
0
28
19
0
0
0
0
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
37
0
0
10
0
0
0
0
0
0
10
% N
% Pro:
0
28
10
10
0
10
10
0
0
19
0
0
0
0
0
% P
% Gln:
0
0
10
0
0
0
0
10
10
0
10
10
10
0
0
% Q
% Arg:
0
0
0
0
0
0
0
10
0
10
19
10
37
10
10
% R
% Ser:
28
10
0
0
0
0
0
28
10
0
0
37
37
19
0
% S
% Thr:
0
0
10
0
0
19
0
0
10
28
0
10
0
10
19
% T
% Val:
37
0
0
0
19
0
10
10
0
0
0
10
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _